Hydroxypropyl Methyl Cellulose (HPMC E5)
Specification: Hydroxypropyl Methyl Cellulose (HPMC E5)
Hs Code: 3912900000
CAS Number: 9004-65-3
packaging: 25kg/drum
MOQ:1000kg
Qty in 20’fcl:9tons
Description
Hydroxypropyl Methyl Cellulose E5 is a low-viscosity cellulose ether derived from natural cellulose through controlled etherification. It appears as a white to slightly off-white powder that dissolves in cold water to form clear solutions, and its non-ionic character keeps it compatible with a wide range of APIs, electrolytes and other excipients. Its low molecular weight makes it the preferred grade for aqueous tablet film coating: solutions spray smoothly, dry quickly and form uniform, elegant films that protect tablets from moisture and light. The same grade performs as a binder in wet granulation and serves as the base material for vegetarian hard capsules. Compliant with USP requirements and produced from natural raw materials, it offers a dependable, plant-derived film former for pharmaceutical and nutraceutical manufacturers worldwide. It is packed in 25 kg fiber drums. The low-viscosity solutions also allow higher coating solids, shortening coating time and energy use in production. In practice coaters prepare 5 to 12 percent aqueous solutions that spray smoothly through standard equipment, and the low viscosity permits fast drying cycles between layers. It also masks objectionable drug tastes with a thin, clean film. The product is manufactured under strict hygiene controls with documented test results for purity, heavy metals and microbial safety, ready for audit when customers require. How HPMC E5 works: hypromellose E5 is a low-viscosity cellulose ether whose solutions spray into fine droplets and dry quickly into uniform, flexible films. The films protect tablets from moisture and light, mask objectionable tastes, and give products an elegant, glossy finish. Because the polymer is non-ionic, it stays compatible with the charged actives and electrolytes that would destabilize ionic polymers. Practical guidance: prepare aqueous coating solutions at practical solids and spray through standard equipment; use it as the base polymer in clear or pigmented film coats; apply it as a granulation binder where clean, gentle bonding is needed; and use it in vegetarian capsule formulations. Quality assurance: produced under USP requirements with viscosity, methoxy and hydroxypropoxy content, pH and microbial limits tested per batch, documented for regulatory files. Packed in 25 kg fiber drums. For pharmaceutical coaters, E5 is the grade that maximizes line throughput with smooth, defect-free finishes. Specification highlights: it is packed in 25kg/drum with a minimum order quantity of 1000kg. Certificates of analysis accompany every shipment, and sample supply, specification customization and flexible payment terms are available for qualified buyers, supported by the standardized seven-step service process from inquiry to after-sales support. Documented quality from batch to batch: every production lot is verified against the full specification - identity, purity, heavy metals and microbiology - before release, and the resulting certificates and batch records travel with each shipment to support qualification and audit. Raw materials are sourced to defined standards, storage follows the conditions stated in the specification, and the product ships in its original, intact packaging. Shelf life and storage requirements are clearly documented, so purchasing, warehouse and quality teams all work from the same reference. This repeatable quality system is what makes the grade dependable for multi-year supply agreements.
Applications
It is primarily used as a film-forming agent for aqueous tablet coating, producing smooth, glossy, protective coats that mask taste and control moisture. As a granulation binder it improves tablet hardness and integrity. It is the key raw material in plant-based hard capsule shells, and it appears in topical gels, suspensions and ophthalmic preparations as a viscosity modifier.
Advantages
The low-viscosity E5 grade gives coaters the best sprayability and fastest drying of the HPMC range, maximizing coating-line throughput with smooth, defect-free finishes. Its plant origin supports vegetarian and clean-label positioning against gelatin alternatives. USP compliance, consistent viscosity control and dependable supply make it the standard choice for aqueous film coating programs.
Specifications
Hydroxypropyl Methylcellulose E5
Comply with USP
| Item | Specifications | Method |
| Appearance | White to slightly off-white fibrous or granular powder | Visual |
| Identification A To E | Conform | USP |
| Methoxy | 28.0-30.0 % | USP |
| Hydroxypropoxy | 7.0-12.0 % | USP |
| Viscosity | 4-6 mPa.s | USP |
| Loss on drying | ≤5.0% | USP |
| Residue on ignition | ≤1.5% | USP |
| PH | 5.0-8.0 | USP |
| Bacterium | ≤1000/g | USP |
| Mold | ≤100/g | USP |
| E.Coli | Absent | USP |
Cas No. 9004-65-3 H.S. Code 39129000
Main Purpose: Tablet film coating, binders,main material of plant capsules.
Package: 25kg/fiber drum
Packing Size: D37cm*H53cm
G.W. 27.5kg
FAQ
Q1 : Do you provide samples? is it free or extra?
Yes, we could offer the sample for free charge but do not pay the cost of freight.
Q2 : Do you accept customization?
We can produce according to your indicators.For specific details, please consult
Q3 : How long is your delivery time?
Generally it is 5-10 days if the goods are in stock. or it is 15-20 days if the goods are not in stock.
Q4 : What is your payment terms?
T/T, L/C, Credit Card, PayPal, Cash.
Accepted Payment Currency:USD,EUR,JPY,CAD,AUD,HKD,GBP,CNY,CHF;
Q5 : How do you ship the products?
By Sea ,By Air ,By courier, Fedex, UPS Etc. It is up to you.
Q6 : What’s the MOQ?
Different products result in different MOQ
For specific details, please consult
What's the order process?
1) Inquiry --- Share your initial requirements with us; we will establish a communication channel and learn about your needs and background.
2) Requirement Alignment --- We discuss technical parameters, application scenarios and regulatory requirements in depth to define the details and delivery standards.
3) Product Confirmation & Quotation --- We provide compliant product options and a detailed quotation covering specifications, pricing and minimum order quantity.
4) Order Processing & Payment Plan --- Contract terms are confirmed and flexible payment arrangements are made, keeping every transaction safe and compliant.
5) Shipping Plan --- We select the optimal shipping route and coordinate customs clearance and insurance to ensure your cargo is dispatched safely and on time.
6) Inspection & Tracking --- We provide quality inspection reports and full logistics tracking, keeping product quality controlled and the shipment fully transparent.
7) After-sales Service --- Technical support, prompt issue response and continuous improvement suggestions build a long-term partnership and ensure your satisfaction.