Hydroxypropyl Methyl Cellulose (HPMC) SH-E4M
Specification: Hydroxypropyl Methyl Cellulose (HPMC SH-E4M)
Hs Code: 3912900000
CAS Number: 9004-65-3
packaging: 25kg/drum
MOQ:1000kg
Qty in 20’fcl:9tons
Description
Hydroxypropyl Methyl Cellulose SH-E4M is a medium-high viscosity cellulose ether derived from natural cellulose. Hydrating in water to substantial viscosity, it is the grade of choice for sustained-release matrices requiring intermediate release kinetics, as well as for strong thickening and protective film applications. Its solutions are clear, smooth and pseudoplastic, spreading easily yet holding structure in gels and suspensions. The polymer is non-ionic and plant-derived, giving it excellent compatibility with charged actives, salts and surfactants across pharmaceutical, food and personal care systems. Compliant with USP requirements and produced with tight viscosity control, it offers dependable performance for controlled-release, thickening and stabilizing applications worldwide. It hydrates smoothly without lumping, simplifying industrial mixing. It is packed in 25 kg fiber drums. Its pseudoplastic flow also gives gels a smooth, non-sticky application feel in topical products. In practice it retards release in matrix systems for drugs that need intermediate kinetics, and its smooth solutions improve the mouthfeel of syrups. It also forms flexible protective films in topical preparations. The product is manufactured under strict hygiene controls with documented test results for purity, heavy metals and microbial safety, ready for audit when customers require. How SH-E4M works: this medium-high viscosity grade hydrates into substantial gel strength, retarding drug release for intermediate dissolution profiles while remaining easy to process. Its solutions are smooth and pseudoplastic - they flow under shear and set when at rest - which gives gels and syrups the elegant, non-stringy texture consumers prefer. Practical guidance: design sustained-release matrices for intermediate kinetics; thicken and stabilize syrups and suspensions; form flexible protective films in topical preparations; and use it in food systems such as sauces and plant-based products. Quality assurance: produced under USP requirements with viscosity, methoxy and hydroxypropoxy content and microbial limits tested per batch, documented for regulatory files. Packed in 25 kg fiber drums. For formulators needing moderate retardation plus liquid-system stability, SH-E4M fills the gap precisely. Specification highlights: it is packed in 25kg/drum with a minimum order quantity of 1000kg. Certificates of analysis accompany every shipment, and sample supply, specification customization and flexible payment terms are available for qualified buyers, supported by the standardized seven-step service process from inquiry to after-sales support. Compliance and quality at a glance: the product is manufactured under the standards referenced in its specification sheet, and every batch is tested for identity, purity, heavy metals and microbiology before release. Batch records, test reports and certificates are kept and supplied for buyer qualification, audit and regulatory filing, and the product is stored and shipped in its original packaging to preserve quality through the supply chain. For industrial buyers, this documented quality system means one qualification covers years of consistent supply, with the specification sheet serving as the contractual reference for every delivery.
Applications
It is used as the hydrophilic matrix in sustained-release tablets targeting intermediate dissolution profiles. Liquid medicines, syrups and suspensions use it as a thickener and stabilizer that improves mouthfeel and physical stability. Topical gels and creams use it for viscosity and film formation, and food applications include sauces, dressings and plant-based products for texture and stabilization.
Advantages
The E4M viscosity range fills the gap between film-coating grades and ultra-high matrix grades, giving formulators a single polymer for moderate release retardation plus thickening and stabilization in liquids. Its smooth, non-stringy rheology improves product elegance in gels and syrups. USP compliance and tight viscosity control keep release profiles and texture consistent from batch to batch.
Specifications
Hypromellose ( Hydroxypropyl Methylcellulose / HPMC ) SH-E4M
Comply with USP
| Item | Specification | Method |
| APPEARANCE | White to slightly off-white fibrous or granular powder. | USP |
| IDENTIFICATION | Conform | USP |
| METHOXY | 28.0-30.0% | USP |
| HYDROXYPROPOXY | 7.0-12.0% | USP |
| APPARENT VISCOSITY(2%) | 3000-5600 mPa.s | USP |
| LOSS ON DRYING | ≤5.0% | USP |
| PH (25℃) | 5.0-8.0 | USP |
| RESIDUE ON IGNITION | ≤1.5% | USP |
| MICROBIAL LIMITS BACTERIUM MOLD & YEAST E.COLI | ≤1000/g ≤100/g Negative | USP |
Storage Conditions: Store in a cool,dry place,away from high temperature and direct sunlight.
Cas No. 9004-65-3 H.S.39129000
Main Purpose: Tablet film coating, binders,main material of plant capsules.
Package: 25kg/fiber drum
Packing Size: D38cm*H53cm
G.W. 27.5kg
FAQ
Q1 : Do you provide samples? is it free or extra?
Yes, we could offer the sample for free charge but do not pay the cost of freight.
Q2 : Do you accept customization?
We can produce according to your indicators.For specific details, please consult
Q3 : How long is your delivery time?
Generally it is 5-10 days if the goods are in stock. or it is 15-20 days if the goods are not in stock.
Q4 : What is your payment terms?
T/T, L/C, Credit Card, PayPal, Cash.
Accepted Payment Currency:USD,EUR,JPY,CAD,AUD,HKD,GBP,CNY,CHF;
Q5 : How do you ship the products?
By Sea ,By Air ,By courier, Fedex, UPS Etc. It is up to you.
Q6 : What’s the MOQ?
Different products result in different MOQ
For specific details, please consult
What's the order process?
1) Inquiry --- Share your initial requirements with us; we will establish a communication channel and learn about your needs and background.
2) Requirement Alignment --- We discuss technical parameters, application scenarios and regulatory requirements in depth to define the details and delivery standards.
3) Product Confirmation & Quotation --- We provide compliant product options and a detailed quotation covering specifications, pricing and minimum order quantity.
4) Order Processing & Payment Plan --- Contract terms are confirmed and flexible payment arrangements are made, keeping every transaction safe and compliant.
5) Shipping Plan --- We select the optimal shipping route and coordinate customs clearance and insurance to ensure your cargo is dispatched safely and on time.
6) Inspection & Tracking --- We provide quality inspection reports and full logistics tracking, keeping product quality controlled and the shipment fully transparent.
7) After-sales Service --- Technical support, prompt issue response and continuous improvement suggestions build a long-term partnership and ensure your satisfaction.